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ABBP-1 abdominal distention biochemical catalyst Bremerhaven dark-field amplitude mode dimsyl etifelmine extreme value of a function free-field response Gaertner vein phenomenon have shadows round the eyes helvella lacunosa afzelius media manipulation meningo-encephalocele mutagenic factors Nishiyoshino polycladose switch grasses symmetry of crystals topotecan(TPT)